PROSS: the Protein Repair One-Stop Shop

Input

Pross Terms V2

Upload PDB? V2

Files V2

Structure info V2

AlphaFold2 confidence V2

Constraints V2

Upload MSA? V2

MSA file V2

MSA V2

Energy function V2

PROSS is a protein stability-design method, and its academic use is free. If academic use of the results leads to applications with commercial potential, please obtain a license to the results from the Weizmann Institute’s technology transfer office Yeda. Commercial users or academic users conducting commercially sponsored research should refer to Scala Biodesign which holds an exclusive license for such uses.

Email address*

Must be a named account belonging to a valid academic domain

First name*

Last name*

Research institute*

Head of research lab*

Full name of the head of research lab

I hereby confirm that I am a current and active member of the academic research institute named above*

Write "Yes" or "No". Commercial users, please contact Scala Biodesign

I hereby confirm that any results of this submission are to be used for academic, non-commercial purposes only and that commercial or for-profit organizations do NOT fund the submission and related research*

Write "Yes" or "No". For sponsored research, please contact Scala Biodesign

I, including on behalf of my institute, accept the Terms and Conditions, whereby, without limitation, the results produced for academic research through the use of PROSS, and any IP rights filed in respect of such results, shall be owned by the technology transfer office of the Weizmann Institute of Science. I am authorized to assume such obligations on behalf of my institute which is named above*

Write "Yes" or "No"

Examples FAQ About PROSS

NEW! a Hands-on tutorial for using the Fleishman lab
protein-optimisation workflows

Selected PROSS & FuncLib citations and patents

Questions and support
Overview & questions: contact us
See also our About PROSS page

Commercial users
Please contact Scala Biodesign

Citation
Please cite Goldenzweig et al. Mol Cell 2016
PMID: 27425410 PDF HTML

Algorithm development
Adi Goldenzweig & Sarel Fleishman
Additional contributions: Jonathan Weinstein
Web interface: Jaime Prilusky and Shi Hoch

Terms and conditions
Use of the output, the variants and their derivatives is subject to the terms and conditions and may be used for academic research only, excluding commercially sponsored research. Accordingly, commercial use of the attached variants or their derivatives is unauthorized without prior written approval by Yeda.